姓名：杨森
职称：讲师
E-Mail：ys@cczu.edu.cn
研究领域：
1、基于深度学习，机器学习，人工智能的计算生物学
2、蛋白质、RNA结构变异位点预测（基于机器学习，深度学习，人工智能）
奖励与荣誉：
1、主持项目
[1]江苏省基础研究计划自然科学基金青年基金项目，BK20230626，lncRNA翻译的多肽作为肿瘤生物标志物的挖掘和分析方法研究，2023.09-2026.08，20万，主持，在研
[2]江苏省“双创博士”项目，JSSCBS20221119，融合多组学知识的异构调控网络癌症标志物挖掘和分析，2022.07-2025.06，15万，主持，在研
[3]植物抗逆高效全国重点实验室开放课题基金项目，SKLPERKF2401，玉米重要抗逆高效性状多组学分子调控网络挖掘与分析研究，2024.01-2025.12，10万，主持，在研
[4]畜禽生物育种全国重点实验室开放课题基金项目，2024SKLAB6-1，基于生物序列网络的小ORF翻译多肽功能研究，2024.01-2025.12，10万，主持，在研
[5]常州市领军型创新人才引进培育项目（基础研究创新类），CQ20230086，基于异构超图多组学调控网络知识的肿瘤生物标志物挖掘与应用，2023.11-2026.11，5万，主持，在研
[6]常州市应用基础研究计划项目，CJ20241083，基于多模态计算模型的胰腺癌长非编码RNA翻译多肽标志物机理研究，2024.05-2026.05，6万，主持，在研
2、发表论文
2025年
[19] CLTAP: A TAP-binding peptide prediction method using pre-trained large language-embedding models
with contrastive learning to enhance contextual co-attention mechanism
Expert Systems with Applications，中科院一区，TOP期刊，IF=7.5
Lun Zhu; Wei Chen; Sen Yang*（通讯作者）
[18] BioSeq_Ksite: Multi-perspective feature-driven prediction of protein succinylation based on an
adaptive attention module with SSBCE loss strategy
International Journal of Biological Macromolecules，中科院二区，TOP期刊，IF=8.4
Lun Zhu; Ziqi Zhang; Sen Yang*（通讯作者）
[17] SORFPP: Enhancing rich sequence-driven information to identify SEPs based on fused
framework on validation datasets
PLOS One，中科院三区，IF=2.9
Hongqi Feng; Qi Nie; Sen Yang*（通讯作者）
2024年
[16] LncSL: A Novel Stacked Ensemble Computing Tool for Subcellular Localization of lncRNA by Amino
Acid-Enhanced Features and Two-Stage Automated Selection Strategy
International Journal of Molecular Sciences，中科院三区，IF=4.9
Lun Zhu; hong chen; Sen Yang*（通讯作者）
[15] EnDM-CPP: A Multi-view Explainable Framework Based on Deep Learning and Machine Learning for
Identifying Cell-Penetrating Peptides with Transformers and Analyzing Sequence Information
Interdisciplinary Sciences: Computational Life Sciences，中科院二区，IF=3.9
Lun Zhu; Zehua Chen; Sen Yang* （通讯作者）
[14] DeepAIP: Deep learning for anti-inflammatory peptide prediction using pre-trained protein
language model features based on contextual self-attention network
International Journal of Biological Macromolecules，中科院二区，TOP期刊，IF=8.4
Lun Zhu; Qingguo Yang; Sen Yang* （通讯作者）
[13] AI4ACEIP: A Computing Tool to Identify Food Peptides with High Inhibitory Activity for ACE by Merged Molecular
Representation and Rich Intrinsic Sequence Information Based on an Ensemble Learning Strategy
Journal of Agricultural and Food Chemistry，中科院一区，TOP期刊，IF=6.1
Sen Yang; Jiaqi Ni; Piao Xu*（第一作者）
[12] LLM4THP: a computing tool to identify tumor homing peptides by molecular and sequence
representation of large language model based on two-layer ensemble model strategy
Amino acids，中科院三区，IF=3.0
Sen Yang; Piao Xu*（第一作者）
[11] HemoDL: Hemolytic peptides prediction by double ensemble engines from Rich sequence-derived
and transformer-enhanced information
Analytical Biochemistry，中科院四区，IF=2.6
Sen Yang; Piao Xu*（第一作者）
[10] PPSNO: A Feature-Rich SNO Sites Predictor by Stacking Ensemble Strategy
from Protein Sequence-Derived Information
Interdisciplinary Sciences: Computational Life Sciences，中科院二区，IF=3.9
Lun Zhu; Liuyang Wang; Zexi Yang; Piao Xu; Sen Yang*（通讯作者）
2023年
[9] LncCat: An ORF attention model to identify LncRNA based on ensemble learning
strategy and fused sequence information
Computational and Structural Biotechnology Journal，中科院三区，IF=4.5
Hongqi Feng; Shaocong Wang; Yan Wang; Xinye Ni; Zexi Yang; Xuemei Hu; Sen Yang*（通讯作者）
[8] DeepDRP: Prediction of intrinsically disordered regions based on integrated view deep learning
architecture from transformer-enhanced and protein information
International Journal of Biological Macromolecules，中科院二区，TOP期刊，IF=8.4
Zexi Yang; Yan Wang; Xinye Ni; Sen Yang*（通讯作者）
[7] AMPFinder: A computational model to identify antimicrobial peptides and their functions
based on sequence-derived information
Analytical Biochemistry，中科院四区，IF=2.6
Sen Yang; Zexi Yang; Xinye Ni*（第一作者）
[6] 4mCBERT: A computing tool for the identification of DNA N4-methylcytosine sites by sequence-
and chemical-derived information based on ensemble learning strategies
International Journal of Biological Macromolecules，中科院二区，TOP期刊，IF=8.4
Sen Yang*; Zexi Yang; Jun Yang（第一作者，通讯作者）
2022年
[5] ACP-check: An anticancer peptide prediction model based on bidirectional long short-term
memory and multi-features fusion strategy
Computers in Biology and Medicine，中科院二区，IF=7.0
Lun Zhu; Chenyang Ye; Xuemei Hu; Sen Yang*; Chenyang Zhu（通讯作者）
[4] IDDLncLoc: Subcellular Localization of LncRNAs Based on a Framework for Imbalanced Data Distributions
Interdisciplinary Sciences: Computational Life Sciences，中科院二区，IF=3.9
Yan Wang; Xiaopeng Zhu; Lili Yang; Xuemei Hu; Kai He;
Cuinan Yu; Shaoqing Jiao; Jiali Chen; Rui Guo; Sen Yang*（通讯作者）
